The priority areas of scientific research conducted at the university are:
• Natural resources of the Fergana Valley and their effective use;
• Regional environmental problems and their study;
• Geoecological foundations for improving the system of protected natural areas;
• Problems of increasing the fertility of irrigated soils widespread in the Fergana Valley;
• The influence of legumes on the biogeocenosis of gray soils of low, medium and high fertility;
• The degree of phenotypic changes of different cotton varieties depending on the growing environment;
• Promising forage crops of the cereal family, widespread in the Uzbek part of the Fergana Valley;
• Development of geoecological foundations for preserving biodiversity;
• Development of geoecological foundations for organizing a system of protected natural areas;
• Conducting hydrometeorological research related to climate change;
• Biomonitoring of the distribution, development, and ecological properties of agricultural crop pests;
• Studying the genetic and geographical patterns of the formation of irrigated soils of the Fergana region, land fund and diagnostics;
• The effect of bentonite agro-ore on the water-physical and chemical properties of sandy soils, wheat yield;
• Application of mathematical methods and information technologies in the field of entomology;
• Bioindication of the state of the environment;
• Studying the patterns of anthropogenic transformation of entomofauna and entomocomplexes;
• Researching raw material plants growing in the Fergana Valley;
• Introduction of unique and scenic plants to the Fergana Valley;
• Study of the species composition of the ichthyofauna of the Fergana Valley;
• Study of optical, photoelectric, deformational and kinetic phenomena of a sharp nature occurring in semiconductors and their structures;
• Extraction of medicinal substances from plants in the chemical industry;
• Creation of technologies for the production of secondary products using local raw materials from chemical industry waste;
• Creation and improvement of highly efficient renewable energy sources;
• Creation of technology for obtaining thermoelectric semiconductors and study of their application areas;
• Decomposable differential equations with special derivatives, probability theory and mathematical statistics;
• Innovative factors and practical means of educating young people in the spirit of high spirituality;
• Formation of a healthy lifestyle of schoolchildren, prevention of psychoneurological disorders in them, study of the negative consequences of cardiovascular activity, smoking and drinking;
• Socio-philosophical problems of forming an information culture in a person in the conditions of globalization;
• Intellectual culture of a person: socio-philosophical analysis;
• Features of the interaction of moral and aesthetic factors in the formation of a person's ecological consciousness;
• History, ethnogenesis and ethnography of the Fergana Valley;
• Archaeology of the Fergana Valley;
• Problems of private ownership, development of small and medium-sized businesses in the transition to a market economy, management of foreign economic activity;
• Methodological foundations of pedagogical design;
• Socio-pedagogical problems of training future teachers for educational work;
• Pedagogical conditions for directing children to social life in the family.
• Fundamentals of the theory of physical education;
• Problems of preschool and primary education;
• Philosophical and spiritual problems of social development;
• Religion and psychology of the individual, the problem of the perfect person;
• Conducting and analyzing sociological research;
• Researching the poetics of a work of art;
• Researching the poetics of a novel;
• Problems of systemic linguistics;
• Theoretical foundations of psycholinguistic research;
• Researching anthropocentric problems;
• Psychological, pedagogical and physiological foundations of physical fitness of youth;
• Managing the public education system and training teachers;
• Creating higher, secondary and primary education methodologies, textbooks and teaching aids.
Research and development work in these areas is carried out mainly within the framework of state budget funds and innovative cooperation agreements concluded with industrial enterprises, as well as state scientific and technical programs and on the basis of economic contracts.